What the Hell Is That?

From OAPedia.com

What The Hell Is That? is an Opie and Anthony bit where people come into the studio and show off physical oddities and deformities. A doctor is on hand to examine each person and let them know if they need to seek professional treatment. The first What The Hell Is That? took place at WNEW on December 7, 2001. The highlight of the bit was when a guy came in who had something wrong with his mouth. The doctor examined him and made a "C" with his hand - cancer! The bit was brought to a dead halt, although apparently the guy turned out to be OK. The incident also led to Jim Norton giving up smoking.

The bit was revived on August 2, 2007, with the highlight being Bob Kelly's puking at one of the contestant's deformities.